Imaging • Chest x-ray. • CT and MRI scans of the abdomen and pelvis. Endoscopy and Biopsy • Cystoscopy . • Sigmoidoscopy . • All women with an abnormal Pap smear or cervical lesions should undergo an office colposcopic examination. A colposcope is an instrument that can magnify the cervix from 7.5 to 15 times. • The definitive diagnosis is made on a biopsy. Early cancers are occasionally diagnosed by a large biopsy of the cervix, known as a cone biopsy . A cervical conization should be done when colposcopy cannot determine if there is not an invasive cancer , when there are no obvious lesions on the cervix and the Pap smear is consistently abnormal, when a colposcopically directed biopsy does not adequately account for abnormal cells found on a Pap smear, when a diagnosis of microinvasion (early invasion) is found on the biopsy or when a cervical intraepithelial neoplasia is identified by a scraping from the cervical canal (endocervical curettage).